An increasing prevalence of overweight and obesity in people living with HIV has been associated with initiation of antiretroviral therapy with integrase strand transfer inhibitors (INSTIs). An off-target inhibition of the endogenous ligand binding to the human melanocortin 4 receptor (MC4R) has been suggested as a potential mechanism for clinical body weight gain following initiation... https://www.bekindtopets.com/limited-deal-Neutral-Checkered-Galaxy-Note-10-Pro-Case-p51042-best-super/
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