We investigated the sleep onset transition in humans from an effective connectivity perspective in a baseline condition (approx. 16 h of wakefulness) and after sleep deprivation (40 h of sustained wakefulness). Using EEG recordings (27 derivations). source localization (LORETA) allowed us to reconstruct the underlying patterns of neuronal activity in various brain regions. https://pipingrockers.shop/product-category/horse-chestnut/