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Evolutionary sequence modeling for discovery of peptide hormones.

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There are currently a large number of "orphan" G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these peptide hormones is a difficult and important problem. We describe a computational framework that models spatial structure along the genomic sequence simultaneously with the temporal evolutionary path structure across speci... https://otsportszones.shop/product-category/nba-packs/
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